Dehydration Alters Human Brain Shape and Activity, Slackens Task Performance

Illustration for dehydration fMRI study. Free sources: Getdrawings.com and Remi Yuan on Unsplash
Aug 23, 2018 - Atlanta, GA
Visible proof that dehydration messes with the brain and cognitive performance.

Buzzing Cancer Drugs into Malignancies in the Brain

An illustration of improved delivery of anti-cancer drugs to malignancies in the brain. On the left half, focused ultrasound agitates microbubbles, which breach the blood-brain barrier, allowing drug molecules to get through. The forces also stir interstitial fluid to circulate the drug, and they also encourage the drug to cross cell membranes more easily into tumor cells. Credit: Massachusetts General Hospital / Georgia Tech / Arvanitis / Askoxylakis
Sep 07, 2018 - Atlanta, GA
As a new anti-cancer drug delivery method heads into phase I clinical trials, researchers explore the tissue-level mechanisms that make it work.

3D-Printed Tracheal Splints Used in Groundbreaking Pediatric Surgery

3D printed tracheal splints are shown around a model of a patient’s trachea. The splints are designed to be absorbed into the body, allowing for expansion of the trachea and bronchus. (Credit: Rob Felt, Georgia Tech)
Sep 18, 2018 - Atlanta, GA
With support from Georgia Tech, Children's Healthcare of Atlanta placed 3D-printed tracheal splints in a pediatric patient.

Delivering Antibodies via mRNA Could Prevent RSV Infection

3D super-resolution microscopy cross-sectional image showing how the engineered antibody aPali works: aPali (green) is expressed on the cell surface and stops RSV particles (pink) from entering the cell.
Nov 05, 2018 - Atlanta, GA
Getting antibodies directly to the lungs protected mice from the virus.

'Demolition Handshakes' Kill Precursor T Cells that Pose Autoimmune Dangers

A healthy human T cell. Credit: National Institute of Allergy and Infectious Disease / National Institutes of Health
Nov 12, 2018 - Atlanta, GA
A mechanism tries to stop our T cells from causing autoimmune disorders, and it's like a tight handshake that kills overly aggressive T cells.

Flu Vaccine Supply Gaps Can Intensify Flu Seasons, Make Pandemics Deadlier

An ambulance in St. Louis, Missouri, picks up a patient believed to be infected with influenza in the 1918-19 Spanish flu pandemic, which killed 50 million people or more worldwide. Credit: National Archives
Jan 07, 2019 - Atlanta, GA
A tweak to our flu vaccine resupply logistics could save thousands of lives

Long-Acting Contraceptive Designed to be Self-Administered Via Microneedle Patch

Regents Professor Mark Prausnitz and postdoctoral research scholar Wei Li examine an experimental microneedle contraceptive skin patch. Designed to be self-administered by women for long-acting contraception, the patch could provide a new family planning option. (Credit: Christopher Moore, Georgia Tech)
Jan 14, 2019 - Atlanta, GA
A new long-acting contraceptive designed to be self-administered by women may provide a new family planning option.

FDA Taps Georgia Tech to Help Reduce Cost of Making Antibiotics

Andreas Bommarius, a professor in the School of Chemical and Biomolecular Engineering, Martha Grover, a professor in the School of Chemical and Biomolecular Engineering, and Ron Rousseau, a professor and Cecil J. "Pete" Silas Chair Emeritus in the School of Chemical and Biomolecular Engineering (Credit: Rob Felt)
Feb 06, 2019 - Atlanta, GA
A team of researchers at the Georgia Institute of Technology has kicked off a three-year federally-funded project to harness new manufacturing technologies and methods in a bid to bring down the cost of making certain antibiotics.

Urine Test Detects Organ Transplant Rejection, Could Replace Needle Biopsies

A T cell, here in purple, makes contact with a transplant organ cell, here in reddish brown. The T cell secretes the enzyme granzyme B, here in gray, which attacks the organ cell. But granzyme B also severs fluorescent signal molecules, in green, from the rejection detecting nanoparticle, in light pink. The signal molecules make their way into the urine, where they give off a fluorescent cue. Georgia Tech / EllaMaru Studio (work for hire, all rights GT, free for distribution).
Feb 19, 2019 - Atlanta, GA
New nanoparticle makes urine glow as soon as T cells initiate an attack on transplanted organs

New Grant Award Supports Research on Early Detection of Ovarian Cancer

The Prevent Cancer Foundation has made a significant grant award to Georgia Tech to advance research on detecting ovarian cancer. The work is led by John McDonald, a professor in the School of Biological Sciences. (Credit: Rob Felt, Georgia Tech)
Feb 26, 2019 - Atlanta, GA
Research on the early detection of ovarian cancer will get a boost from a new award from the Prevent Cancer Foundation.
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